Screen Shot 2014-07-21 at 12.33.24 PM

The patch-clamp amplifier is a ubiquitous tool for characterizing ion-channel activity. For the screening of pharmaceutical compounds or the characterization of expressed channels, high-throughput patch-clamp systems are being developed, where recordings are made from cells in each well of a 96 or 384-well plate. In these systems the recording is made not with a glass pipette, but from a planar electrode at the bottom of each well.

Download (PDF, 1.47MB)