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The patch-clamp amplifier is a ubiquitous tool for characterizing ion-channel activity. For the screening of pharmaceutical compounds or the characterization of expressed channels, high-throughput patch-clamp systems are being developed, where recordings are made from cells in each well of a 96 or 384-well plate. In these systems the recording is made not with a glass pipette, but from a planar electrode at the bottom of each well.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978236/